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Palonosetron hydrochloride
CAS No. 135729-62-3
Palonosetron hydrochloride( Aloxi | RS 25259-197 )
Catalog No. M11463 CAS No. 135729-62-3
Palonosetron (INN, trade name Aloxi) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | 42 | In Stock |
|
| 50MG | 50 | In Stock |
|
| 100MG | 77 | In Stock |
|
| 200MG | 122 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePalonosetron hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionPalonosetron (INN, trade name Aloxi) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).
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DescriptionPalonosetron (INN, trade name Aloxi) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). It is the most effective of the 5-HT3 antagonists in controlling delayed CINV nausea and vomiting that appear more than 24 hours after the first dose of a course of chemotherapy and is the only drug of its class approved for this use by the U.S. Food and Drug Administration. As of 2008, it is the most recent 5-HT3 antagonist to enter clinical use.
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In Vitro——
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In Vivo——
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SynonymsAloxi | RS 25259-197
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PathwayEndocrinology/Hormones
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Target5-HT Receptor
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Recptor5-HT
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Research AreaCardiovascular Disease
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Indication——
Chemical Information
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CAS Number135729-62-3
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Formula Weight332.87
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Molecular FormulaC19H24N2O·HCl
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Purity>98% (HPLC)
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SolubilityWater: 67 mg/mL (201.27 mM)
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SMILESC1C[C@@H]2CN(C(=O)C3=C2C(=CC=C3)C1)[C@@H]4CN5CCC4CC5.Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Grunberg SM, Koeller JM. Expert Opin PharmacOthers. 2003 Dec;4(12):2297-303.
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