Palonosetron hydrochloride

Research use only, not for human use.

Palonosetron (INN, trade name Aloxi) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).

Palonosetron (INN, trade name Aloxi) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). It is the most effective of the 5-HT3 antagonists in controlling delayed CINV nausea and vomiting that appear more than 24 hours after the first dose of a course of chemotherapy and is the only drug of its class approved for this use by the U.S. Food and Drug Administration. As of 2008, it is the most recent 5-HT3 antagonist to enter clinical use.

Aloxi; RS 25259-197

Endocrinology/Hormones

5-HT Receptor

5-HT

Cardiovascular Disease

——

135729-62-3

332.87

C19H24N2O·HCl

>98%(HPLC)

Water: 67 mg/mL (201.27 mM)

C1C[C@@H]2CN(C(=O)C3=C2C(=CC=C3)C1)[C@@H]4CN5CCC4CC5.Cl

——

(-20℃)

With Ice Pack

≥ 2 years