Palonosetron hydrochloride

CAS No. 135729-62-3

Palonosetron hydrochloride ( Aloxi; RS 25259-197 )

Catalog No. M11463 CAS No. 135729-62-3

Palonosetron (INN, trade name Aloxi) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
25MG 42 In Stock
50MG 50 In Stock
100MG 77 In Stock
200MG 122 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Palonosetron hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Palonosetron (INN, trade name Aloxi) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).
  • Description
    Palonosetron (INN, trade name Aloxi) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). It is the most effective of the 5-HT3 antagonists in controlling delayed CINV nausea and vomiting that appear more than 24 hours after the first dose of a course of chemotherapy and is the only drug of its class approved for this use by the U.S. Food and Drug Administration. As of 2008, it is the most recent 5-HT3 antagonist to enter clinical use.
  • Synonyms
    Aloxi; RS 25259-197
  • Pathway
    Endocrinology/Hormones
  • Target
    5-HT Receptor
  • Recptor
    5-HT
  • Research Area
    Cardiovascular Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    135729-62-3
  • Formula Weight
    332.87
  • Molecular Formula
    C19H24N2O·HCl
  • Purity
    >98%(HPLC)
  • Solubility
    Water: 67 mg/mL (201.27 mM)
  • SMILES
    C1C[C@@H]2CN(C(=O)C3=C2C(=CC=C3)C1)[C@@H]4CN5CCC4CC5.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Grunberg SM, Koeller JM. Expert Opin PharmacOthers. 2003 Dec;4(12):2297-303.
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